Format

Send to

Choose Destination
Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26809. Epub 2017 Sep 14.

Consensus and controversies regarding the treatment of rhabdomyosarcoma.

Author information

1
Division of Pediatric Hematology-Oncology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
2
Division of Pediatric Oncology, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland.
3
Center for Cancer and Blood Disorders, Connecticut Children's Medical Center, Hartford, Connecticut.
4
Sarcoma Department, Adolescent and Young Adult Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
5
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska.
6
Division of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
7
Jimmy Everest Section of Pediatric Hematology/Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
8
Division of Pediatric Hematology/Oncology, University of Kentucky, Lexington, Kentucky.

Abstract

Optimal treatment of rhabdomyosarcoma (RMS) requires multidisciplinary approach, incorporating chemotherapy with local control. Although current therapies are built on cooperative group trials, a comprehensive standard of care to guide clinical decision making has been lacking, especially for relapsed patients. Therefore, we assembled a panel of pediatric and adolescent and young adult sarcoma experts to develop treatment guidelines for managing RMS and to identify areas in which further research is needed. We created algorithms incorporating evidence-based care for patients with RMS, emphasizing the importance of clinical trials and close integration of all specialties involved in the care of these patients.

KEYWORDS:

adolescent and young adult; chemotherapy; pediatric; rhabdomyosarcoma; sarcoma

PMID:
28905489
DOI:
10.1002/pbc.26809
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center