Format

Send to

Choose Destination
Int J Mol Sci. 2017 Sep 12;18(9). pii: E1949. doi: 10.3390/ijms18091949.

The Role of Vitamin D in Thyroid Diseases.

Kim D1,2.

Author information

1
Division of Endocrinology, Department of Internal Medicine, Dankook University College of Medicine, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 330-714, Korea. dh9070@hanmail.net.
2
Department of Kinesiologic Medical Science, Graduate, Dankook University, Cheonan 330-714, Korea. dh9070@hanmail.net.

Abstract

The main role of vitamin D is regulating bone metabolism and calcium and phosphorus homeostasis. Over the past few decades, the importance of vitamin D in non-skeletal actions has been studied, including the role of vitamin D in autoimmune diseases, metabolic syndromes, cardiovascular disease, cancers, and all-cause mortality. Recent evidence has demonstrated an association between low vitamin D status and autoimmune thyroid diseases such as Hashimoto's thyroiditis and Graves' disease, and impaired vitamin D signaling has been reported in thyroid cancers. This review will focus on recent data on the possible role of vitamin D in thyroid diseases, including autoimmune thyroid diseases and thyroid cancers.

KEYWORDS:

Graves’ disease; Hashimoto’s thyroiditis; autoimmune thyroid disease; thyroid cancer; vitamin D

PMID:
28895880
PMCID:
PMC5618598
DOI:
10.3390/ijms18091949
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center