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Laryngoscope Investig Otolaryngol. 2016 Oct 20;1(6):150-153. doi: 10.1002/lio2.35. eCollection 2016 Dec.

Serum vitamin D and recurrent benign paroxysmal positional vertigo.

Author information

1
Yonseimirae Otorhinolaryngology Clinic (g.i.r.) Paju Republic of Korea.

Abstract

OBJECTIVES:

The objective of the present study was to examine the effects of serum 25-hydroxyvitamin D concentrations on patients diagnosed with benign paroxysmal positional vertigo (BPPV) on BPPV recurrence.

STUDY DESIGN:

Case series.

METHODS:

A retrospective review of 232 patients diagnosed with BPPV visiting the clinic between June 2014 and June 2015 was performed. All patients underwent a complete otolaryngological, audiologic, and neurologic evaluation. The appropriate particle-repositioning maneuver was performed depending on the type of BPPV. The patients were divided into the recurrence group and the nonrecurrence group. Age, gender, follow-up period, type of BPPV, and vitamin D concentrations in the two groups were compared and analyzed through binary logistic regression analyses.

RESULTS:

The average follow-up period after treatment was 10.2 months. Forty-one (17.7%) of 232 patients suffered a recurrence during the follow-up period. The mean vitamin D concentration of 191 patients who did not suffer any recurrence was 16.63 ng/mL, whereas that of 41 patients who suffered a recurrence was 13.64 ng/mL. This difference in vitamin D concentrations was statistically significant (P < 0.019). The patients' age, gender, follow-up period, and type of BPPV had no statistically significant impact.

CONCLUSION:

Vitamin D is assumed to affect BPPV as a recurrence factor independent of age, gender, follow-up period, and type of BPPV.

LEVEL OF EVIDENCE:

4.

KEYWORDS:

Vitamin D; benign paroxysmal positional vertigo; logistic regression; recurrence

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