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Cell. 2017 Sep 7;170(6):1055-1056. doi: 10.1016/j.cell.2017.08.031.

Converting Cold into Hot Tumors by Combining Immunotherapies.

Author information

1
The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, the Netherlands. Electronic address: j.haanen@nki.nl.

Abstract

In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62% response rate in patients with metastatic melanoma, accompanied by enhanced T cell infiltration in virus-injected lesions.

PMID:
28886376
DOI:
10.1016/j.cell.2017.08.031
[Indexed for MEDLINE]
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