Format

Send to

Choose Destination
Am J Surg. 2018 Jan;215(1):144-150. doi: 10.1016/j.amjsurg.2017.08.019. Epub 2017 Sep 1.

Impact of screening for metabolic syndrome on the evaluation of obese living kidney donors.

Author information

1
Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
2
Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
3
Department of Surgery, University of Michigan, Ann Arbor, MI, USA. Electronic address: rssung@umich.edu.

Abstract

BACKGROUND:

We report our experience with metabolic syndrome screening for obese living kidney donor candidates to mitigate the long-term risk of CKD.

METHODS:

We retrospectively reviewed 814 obese (BMI≥30) and 993 nonobese living kidney donor evaluations over 12 years. Using logistic regression, we explored interactions between social/clinical variables and candidate acceptance before and after policy implementation.

RESULTS:

Obese donor candidate acceptance decreased after metabolic syndrome screening began (56.3%, 46.3%, p < 0.01), while nonobese candidate acceptance remained similar (59.6%, 59.2%, p = 0.59). Adjusting for age, gender, race, BMI, and number of prior evaluations, acceptance of obese candidates decreased significantly more than nonobese (p = 0.025). In candidates without metabolic syndrome, there was no significant change in how age, sex, race, or BMI affected a donor candidate's probability of acceptance.

CONCLUSION:

Metabolic syndrome screening is a simple stratification tool for centers with liberal absolute BMI cut-offs to exclude potentially higher-risk obese candidates.

KEYWORDS:

Complex kidney donor; Kidney transplant; Living kidney donation; Metabolic syndrome; Obesity

PMID:
28882358
DOI:
10.1016/j.amjsurg.2017.08.019
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center