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J Korean Med Sci. 2017 Oct;32(10):1727-1730. doi: 10.3346/jkms.2017.32.10.1727.

Primary Pulmonary Extranodal Natural Killer/T-cell Lymphoma, Nasal Type Presenting as Diffuse Ground Glass Opacities: a Case Report.

Author information

1
Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Institute of Chest Diseases, Yonsei University College of Medicine, Seoul, Korea.
2
Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
3
Division of Hematology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
4
Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Institute of Chest Diseases, Yonsei University College of Medicine, Seoul, Korea. dobie@yuhs.ac.

Abstract

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTCL) is a rare type of lymphoma that accounts for only 5%-18% of all cases of non-Hodgkin lymphoma (NHL). In published series, 60%-90% of NK/T-cell lymphomas are localized to the nasal and upper airway. We describe a 55-year man who presented with cough, sputum, dyspnea on exertion, and a chest computed tomography scan shows diffuse ground glass opacities (GGOs), suggestive of an interstitial lung disease. He was treated with a corticosteroid and his symptoms improved. However, when the corticosteroid was tapered, his symptoms recurred. The patient underwent a surgical lung biopsy and ENKTCL was diagnosed. We present this case because ENKTCL involving only the lung is very rare but very informative. To our knowledge, our patient is the first case that primary pulmonary ENKTCL is presented with GGOs.

KEYWORDS:

Ground Glass Opacities; Lung Diseases, Interstitial; Lung Involvement; Lymphoma, Extranodal NK-T-Cell

PMID:
28875622
PMCID:
PMC5592192
DOI:
10.3346/jkms.2017.32.10.1727
[Indexed for MEDLINE]
Free PMC Article

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