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Food Chem. 2018 Jan 15;239:588-597. doi: 10.1016/j.foodchem.2017.06.149. Epub 2017 Jun 29.

In vitro investigation of anticancer and ACE-inhibiting activity, α-amylase and α-glucosidase inhibition, and antioxidant activity of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk.

Author information

1
Food Science Department, College of Food and Agriculture, United Arab Emirates University (UAEU), PO Box 1555, Al Ain, United Arab Emirates. Electronic address: mutamed.ayyash@uaeu.ac.ae.
2
Food Science Department, College of Food and Agriculture, United Arab Emirates University (UAEU), PO Box 1555, Al Ain, United Arab Emirates.
3
Food Science and Technology Programme, Department of Chemistry, National University of Singapore, S14 Level 5, Science Drive 2, 117542, Singapore.

Abstract

This study aimed to investigate in vitro the health-promoting benefits (anticancer activity, α-amylase and α-glucosidase inhibition, angiotensin-converting-enzyme (ACE)-inhibition, antioxidant and proteolytic activity) of camel milk fermented with indigenous probiotic strains of Lactobacillus spp., compared with fermented bovine milk. The three camel milk probiotic strains Lb. reuteri-KX881777, Lb. plantarum-KX881772, Lb. plantarum-KX881779 and a control strain Lb. plantarum DSM2468 were employed to ferment camel and bovine milks separately. The proteolytic and antioxidant activity of water soluble extracts (WSEs) from all fermented camel milks were higher than those of fermented bovine milk. α-Amylase inhibition of WSEs were >34% in both milk types fermented with all strains during storage periods, except the WSE of camel milk fermented by Lp.K772. The highest ACE-inhibition of the WSE from camel milk fermented by Lr.K777 was >80%. The proliferations of Caco-2, MCF-7 and HELA cells were more inhibited when treated with the WSE of fermented camel milk.

KEYWORDS:

1,1-Diphenyl-2-picrylhydrazyl DPPH (PubChem CID: 2735032); ACE-inhibition; Anticancer; Camel milk; Fermented; Hippuryl-histidyl-leucine (PubChem CID: 94418); Probiotics; o-Phthalaldehyde (PubChem CID: 4807); p-Nitrophenyl α-d-glucopyranoside (PubChem CID: 102764)

PMID:
28873609
DOI:
10.1016/j.foodchem.2017.06.149
[Indexed for MEDLINE]

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