Format

Send to

Choose Destination
Head Neck. 2017 Nov;39(11):2232-2240. doi: 10.1002/hed.24886. Epub 2017 Sep 4.

Quality of life after thyroidectomy in patients with nontoxic nodular goiter: A prospective cohort study.

Author information

1
Department of ORL Head & Neck Surgery, Odense University Hospital, Odense, Denmark.
2
Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
3
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark.
4
OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark.

Abstract

BACKGROUND:

Using the thoroughly validated Thyroid-Related Quality-of-Life Patient-Reported Outcome (ThyPRO) questionnaire, the purpose of this study was to investigate changes in disease-specific quality of life (QOL) after surgical treatment in patients with benign nontoxic multinodular goiters.

METHOD:

Patients with goiters scheduled for thyroid surgery (n = 106) and individuals from the general population (n = 739) were studied. The ThyPRO data before, 3 months, and 6 months after surgery were compared with normative scores from the general population using a linear mixed model and t tests.

RESULTS:

Before surgery, patients with goiters experienced poorer scores on all scales compared to the general population. After surgery, moderate to large improvements were seen in goiter symptoms, tiredness, anxiety, and overall QOL. After surgery, all scales returned to values equal to the general population. The degree of anxiety was, in fact, lower than in the general population.

CONCLUSION:

Thyroid surgery leads to significant benefit among patients with benign nontoxic goiters by restoring QOL equal to that in the general population.

KEYWORDS:

Thyroid-Related Quality-of-Life Patient-Reported Outcome (ThyPRO); goiter; quality of life; surgery; thyroid

PMID:
28872214
DOI:
10.1002/hed.24886
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center