Format

Send to

Choose Destination
Nat Neurosci. 2017 Oct;20(10):1404-1412. doi: 10.1038/nn.4635. Epub 2017 Sep 4.

Seeing faces is necessary for face-domain formation.

Author information

1
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Here we report that monkeys raised without exposure to faces did not develop face domains, but did develop domains for other categories and did show normal retinotopic organization, indicating that early face deprivation leads to a highly selective cortical processing deficit. Therefore, experience must be necessary for the formation (or maintenance) of face domains. Gaze tracking revealed that control monkeys looked preferentially at faces, even at ages prior to the emergence of face domains, but face-deprived monkeys did not, indicating that face looking is not innate. A retinotopic organization is present throughout the visual system at birth, so selective early viewing behavior could bias category-specific visual responses toward particular retinotopic representations, thereby leading to domain formation in stereotyped locations in inferotemporal cortex, without requiring category-specific templates or biases. Thus, we propose that environmental importance influences viewing behavior, viewing behavior drives neuronal activity, and neuronal activity sculpts domain formation.

PMID:
28869581
PMCID:
PMC5679243
DOI:
10.1038/nn.4635
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center