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Diabetes Metab Syndr. 2018 Jan - Mar;12(1):17-21. doi: 10.1016/j.dsx.2017.07.044. Epub 2017 Aug 23.

The association between hematological parameters and metabolic syndrome in Iranian men: A single center large-scale study.

Author information

1
Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran.
2
Social Determinants of Health Research Center, Occupational Medicine Center, Urmia University of Medical Sciences, Urmia, Iran.
3
Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
4
Social Determinants of Health Research Center, Occupational Medicine Center, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: irajmohebbi@umsu.ac.ir.
5
Vice-Chancellor of Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
6
Road Maintenance and Transportation Organization, Tehran, Iran.

Abstract

AIMS:

Some studies have demonstrated that metabolic syndrome is associated with hematological parameters. The present study explores the relationship between hematological parameters and numbers of metabolic syndrome conditions in Iranian men.

METHODS:

This cross-sectional study included 11,114 participants who were professional drivers of commercial motor vehicles, and were enrolled in the Iranian Health Surveys between 2014 and 2016. Diagnosis of metabolic syndrome was made according to International Diabetes Federation criteria. Clinical data, including anthropometric measurements and serum parameters, were collected. Odds ratios for hematological parameters and metabolic syndrome were calculated using binary logistic regression models.

RESULTS:

We found that hemoglobin; platelet, and white blood cell counts increased with increasing numbers of metabolic syndrome components (p<0.05 for all). The odds ratio of metabolic syndrome significantly increased across successive quartiles of platelet (1.00, 1.25, 1.29, and 1.51) and white blood cell counts (1.00, 1.51, 1.79, and 2.11) with the lowest quartile as the referent group. Similar associations for hemoglobin and hematocrit in the top quartile were also observed. We did not observe any significant difference in the mean of neutrophil count, mean platelet volume (MPV), red cell distribution width, or platelet distribution width among participants with or without metabolic syndrome.

CONCLUSIONS:

Our findings indicate that high levels of major hematological parameters such as hemoglobin, hematocrit, as well as platelet and white blood cell counts could be novel indicators for the development of metabolic syndrome.

KEYWORDS:

Hematological parameters; Iran; Metabolic syndrome; a cross sectional study

PMID:
28869150
DOI:
10.1016/j.dsx.2017.07.044
[Indexed for MEDLINE]

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