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Case Rep Oncol. 2017 Jul 11;10(2):627-633. doi: 10.1159/000478004. eCollection 2017 May-Aug.

Successful Yttrium-90 Microsphere Radioembolization for Hepatic Metastases of Prostate Cancer.

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Department of Radiology, University Hospital of Cologne, Cologne, Germany.
Practice for Oncology and Hematology, Cologne, Germany.
Department of Urology, University Hospital of Cologne, Cologne, Germany.
Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany.


Prostate cancer is the most common solid tumor malignancy worldwide with an estimated 180,000 new cases of prostate cancer and 26,000 deaths in the USA in 2016. Although significant advances in the treatment of prostate cancer have recently been made, the treatment of metastatic disease remains a challenge. With visceral metastases marking more advanced tumor stages, liver involvement is associated with the worst prognosis. So far, no locoregional treatment regimens for the management of liver metastases of prostatic cancer exist. Herein, we report for the first time a successful treatment of hepatic metastases of prostatic cancer using radioembolization with selective intra-arterial administration of Yttrium-90 resin microspheres.


Hepatic metastases; Prostate cancer; Radioembolization; Selective internal radiation therapy

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