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J Hosp Infect. 2017 Dec;97(4):371-375. doi: 10.1016/j.jhin.2017.08.019. Epub 2017 Sep 1.

Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris.

Author information

1
Public Health England, National Infection Service, Porton Down, Salisbury, UK. Electronic address: ginny.moore@phe.gov.uk.
2
Department of Microbiology, Royal Brompton Hospital and Harefield NHS Foundation Trust, London, UK.
3
National Mycology Reference Laboratory, Public Health England South-West, Bristol, UK.
4
Public Health England, National Infection Service, Colindale, London, UK; Department of Infection, Royal Free Hospital NHS Foundation Trust, London, UK.

Abstract

Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.

KEYWORDS:

Candida auris; Chlorhexidine gluconate; Chlorine; Povidone-iodine; Quantitative suspension test

PMID:
28865738
DOI:
10.1016/j.jhin.2017.08.019
[Indexed for MEDLINE]

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