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Head Neck. 2017 Nov;39(11):2276-2282. doi: 10.1002/hed.24898. Epub 2017 Aug 26.

Clinicopathological characteristics and outcomes of squamous cell carcinoma of the tongue in different age groups.

Author information

1
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
2
Central Laboratory, Peking University School and Hospital of Stomatology, Beijing, China.

Abstract

BACKGROUND:

The clinicopathological features and outcomes of squamous cell carcinoma (SCC) of the tongue in patients of different age groups remain debatable.

METHODS:

Medical records of 457 patients with tongue SCC were reviewed, grouped by age, followed up, and compared.

RESULTS:

Sex and TNM stage showed no intergroup differences. Tongue SCC in patients ≤30 years had the most advanced TNM classification and greatest proportion of poorly differentiation tumors. Both disease-free survival (DFS) and disease-specific survival (DSS) showed no statistically significant difference between the youngest and the oldest groups (P = .605 and P = .520). However, there was a tendency of higher death rate caused by recurrence or metastasis in the youngest group compared with the others (91.7% vs 75.4% and 77.4%).

CONCLUSION:

Young patients had a tendency of higher death rate caused by recurrence or metastasis than middle-age and older patients; therefore, a larger case sample is needed for further confirmation.

KEYWORDS:

oral cancer; squamous cell carcinoma; survival; tongue; young people

PMID:
28842932
DOI:
10.1002/hed.24898
[Indexed for MEDLINE]

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