Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Neurol. 1987 Apr;21(4):349-52.

Linkage of adrenoleukodystrophy to a polymorphic DNA probe.

Abstract

Linkage studies between X-linked adrenoleukodystrophy and a cloned deoxyribonucleic acid fragment (St14), which detects polymorphisms in the distal end of the long arm of the X chromosome (Xq27-28), have shown no recombination in six families. The lod score for these data (and another kindred reported earlier is 13.766 at recombination fraction (theta) = 0.0. These data permit assignment of adrenoleukodystrophy carrier status in family members at risk, supplementing the chemical measurement of very-long-chain fatty acids.

PMID:
2883927
DOI:
10.1002/ana.410210406
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center