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Top Antivir Med. 2017 Jul/Aug;25(3):103-109.

Understanding Hepatitis C Virus Drug Resistance: Clinical Implications for Current and Future Regimens.

Author information

1
Denver Health Medical Center and The University of Colorado, Denver, CO, USA.
2
Zuckerberg San Francisco General, University of California San Francisco, San Francisco, CA, USA.

Abstract

Viral resistance to direct-acting antiviral drugs may impact their effectiveness during treatment of hepatitis C virus (HCV) infection. Most data on HCV drug resistance concern genotypes 1 and 3. The clinical impact of resistance to HCV nonstructural protein 5A (NS5A) inhibitors and a practical approach to indications and methods for resistance testing are discussed.

PMID:
28820725
PMCID:
PMC5935211
[Indexed for MEDLINE]
Free PMC Article

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