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Childs Nerv Syst. 2018 Jan;34(1):165-167. doi: 10.1007/s00381-017-3571-2. Epub 2017 Aug 16.

Intradural lumbosacral malignant extrarenal rhabdoid tumor: a case report.

Author information

1
Department of Neurosurgery, Wayne State University, 4201 St. Antoine blvd, Suite 6E, Neurosurgery, Detroit, MI, 48201, USA. Jgarling@med.wayne.edu.
2
Wayne State University School of Medicine, Detroit, MI, USA.
3
Department of Neurosurgery, Wayne State University, 4201 St. Antoine blvd, Suite 6E, Neurosurgery, Detroit, MI, 48201, USA.
4
Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
5
Department of Neurosurgery, Children's Hospital of Michigan, Detroit, MI, USA.

Abstract

BACKGROUND:

Rhabdoid tumors are highly malignant tumors predominantly affecting the pediatric population. When these tumors occur outside of the kidneys, they are referred to as malignant extrarenal rhabdoid tumors (MERT), a rare highly aggressive subtype. Less commonly, these tumors involve the neuro-axis.

OBJECTIVE:

Here we present a case of a 15-year-old girl with intradural MERT of the lumbosacral spine who presented with back pain, sudden worsening of lower extremity strength, and complete loss of bowel and bladder control.

RESULTS:

The patient's tumor showed loss of INI-1 and negative staining for cytokeratin AE1AE3, CD99, and SOX10.

CONCLUSIONS:

To our knowledge, there are no previous case reports of MERT with intradural lumbosacral spinal involvement.

KEYWORDS:

Intradural; Lumbar; MERT; Malignant extrarenal rhabdoid tumor; Pediatric; Sacral

PMID:
28815340
DOI:
10.1007/s00381-017-3571-2
[Indexed for MEDLINE]

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