Format

Send to

Choose Destination
J Nat Sci. 2017 Jul;3(7). pii: e408.

Pathways to Genome-targeted Therapies in Serous Ovarian Cancer.

Author information

1
Division of Gynecologic Oncology, Department of Reproductive Medicine, UCSD School of Medicine and UCSD Moores Cancer Center, 3855 Health Sciences Drive, La Jolla, CA 39216, USA.

Abstract

Genome sequencing technologies and corresponding oncology publications have generated enormous publicly available datasets for many cancer types. While this has enabled new treatments, and in some limited cases lifetime management of the disease, the treatment options for serous ovarian cancer remain dismal. This review summarizes recent advances in our understanding of ovarian cancer, with a focus on heterogeneity, functional genomics, and actionable data.

KEYWORDS:

genomics; heterogeneity; ovarian cancer; pathway analysis; targeted therapy

PMID:
28815209
PMCID:
PMC5555645

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center