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BMC Infect Dis. 2017 Aug 15;17(1):572. doi: 10.1186/s12879-017-2677-1.

Secondary organizing pneumonia following viral pneumonia caused by severe influenza B: a case report and literature reviews.

Author information

1
Department of Clinical Infectious Diseases, Aichi Medical University School of Medicine, 〒480-1195 1-1 Yazakokarimata, Nagakute, Aichi, Japan.
2
Department of Pathology, Nagoya Ekisaikai Hospital, Nagoya, Aichi, Japan.
3
Department of Clinical Infectious Diseases, Aichi Medical University School of Medicine, 〒480-1195 1-1 Yazakokarimata, Nagakute, Aichi, Japan. mikamo@aichi-med-u.ac.jp.

Abstract

BACKGROUND:

Some reported that organizing pneumonia (OP) may occur after influenza A infections including swine-origin influenza A (H1N1). However, OP associated with influenza B infection has never been reported. We report the first case of secondary OP associated with viral pneumonia caused by influenza B.

CASE PRESENTATION:

A 23-year old woman was diagnosed as viral pneumonia caused by type B influenza. Despite of antiviral therapy, abnormal chest shadows were not improved. Bronchoscopy and transbronchial lung biopsy showed organizing pneumonia due to viral pneumonia caused by influenza B. Corticosteroid therapy was started at 30 mg daily (0.5 mg/kg), and the dose was reduced to 25, 20, 15 or 10 mg per day every month with symptomatic and radiological resolution. Even after corticosteroid therapy was discontinued, we did not confirm disease recurrence.

CONCLUSIONS:

Physicians should be aware of the possibility for SOP and severe viral pneumonia even in case of type B as well as type A influenza infections.

KEYWORDS:

Influenza pneumonia; Organizing pneumonia; Type B influenza virus

PMID:
28810835
PMCID:
PMC5558726
DOI:
10.1186/s12879-017-2677-1
[Indexed for MEDLINE]
Free PMC Article

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