Mechanical reinforcement of bioceramics scaffolds via fracture energy dissipation induced by sliding action of MoS2 nanoplatelets

Cijun Shuai; Hang Sun; Chengde Gao; Pei Feng; Wang Guo; Youwen Yang; Mingchun Zhao; Sheng Yang; Fulai Yuan; Shuping Peng

doi:10.1016/j.jmbbm.2017.07.027

Mechanical reinforcement of bioceramics scaffolds via fracture energy dissipation induced by sliding action of MoS₂ nanoplatelets

J Mech Behav Biomed Mater. 2017 Nov:75:423-433. doi: 10.1016/j.jmbbm.2017.07.027. Epub 2017 Jul 20.

Authors

Cijun Shuai¹, Hang Sun², Chengde Gao², Pei Feng², Wang Guo², Youwen Yang², Mingchun Zhao³, Sheng Yang⁴, Fulai Yuan⁵, Shuping Peng⁶

Affiliations

¹ State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, Hunan 410083, China; Jiangxi University of Science and Technology, Ganzhou, Jiangxi 341000, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, Hunan 410008, China.
² State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, Hunan 410083, China.
³ School of Material Science and Engineering, Central South University, Changsha, Hunan 410083, China.
⁴ Human Reproduction Center, Shenzhen Hospital of Hongkong University, Shenzhen, Guangdong 518053, China.
⁵ Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address: yuanfl@yahoo.com.
⁶ The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan 410078, China. Electronic address: shuping@csu.edu.cn.

PMID: 28806647
DOI: 10.1016/j.jmbbm.2017.07.027

Abstract

The inherent brittleness of bioceramics restricts their applications in load bearing implant, although they possess good biocompatibility and bioactivity. In this study, molybdenum disulfide nanoplatelets (MSNPs) were used to reinforce bioceramics (Mg₂SiO₄/CaSiO₃) scaffolds fabricated by selective laser sintering (SLS). The fracture mode of scaffolds was transformed from transgranular to mixed trans- and intergranular. It could be explained that MSNPs could slide easily due to their weak interlayer van der Waals interactions and provide elastic deformation due to their high elastic modulus. Such sliding action and elastic deformation synergistically induced crack bridging, crack deflection, pull-out and break of MSNPs. Those effects effectively increased the fracture energy dissipation and strain capacity as well as changed the fracture mode, contributing to high fracture toughness and compression strength. Additionally, the scaffolds with MSNPs not only formed a bioactive apatite layer in simulated body fluid, but also supported cell adhesion and proliferation.

Keywords: Bioceramics scaffold; Biocompatibility; Mechanical properties; Molybdenum disulfide nanoplatelets.

MeSH terms

Biocompatible Materials / analysis*
Body Fluids
Cell Adhesion
Ceramics / analysis*
Compressive Strength
Disulfides
Elastic Modulus
Molybdenum
Nanoparticles
Tissue Scaffolds*

Substances

Biocompatible Materials
Disulfides
Molybdenum
molybdenum disulfide