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Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(7):36-42. doi: 10.17116/jnevro20171177136-42.

[Preventive treatment of tension headache in children and adolescents].

[Article in Russian; Abstract available in Russian from the publisher]

Author information

1
Pirogov Russian National Research Medical University, Moscow, Russia.

Abstract

in English, Russian

AIM:

To assess the efficacy of noophen (γ-amino-β-phenylbutyric acid hydrochloride) in the preventive treatment of tension-type headache (TTH) in children and adolescents.

MATERIAL AND METHODS:

The study included 30 patients with TTH, aged from 8 to 16 years, treated with noophen in dose of 15-20 mg/kg per day (2-3 times perorally) during 2 month. Before and during the treatment characteristics of headache, its influence on daily activities were assessed with HIT-6 and PedMIDAS, anxiety disorders were assessed with SCAS, the dynamics of sleep disturbances in children were evaluated.

RESULTS AND CONCLUSION:

A significant decrease in the frequency, duration and intensity of TTH as well as positive changes in daily life activities and reduction of anxiety and sleep disorders manifestations, which are the risk factors for TTH, were demonstrated during the treatment with noophen. Starting from the first month of treatment, there was a significant decrease in the number of days completely lost because of headache and days with the reduced activity (a decrease in the productivity by >50%).

KEYWORDS:

adolescents; children; noophen; preventive treatment; tension headache

PMID:
28805758
DOI:
10.17116/jnevro20171177136-42
[Indexed for MEDLINE]

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