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Euro Surveill. 2017 Aug 3;22(31). pii: 30589. doi: 10.2807/1560-7917.ES.2017.22.31.30589.

Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.

Author information

1
Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
2
Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
3
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Perugia, Italy.
4
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Reggio Emilia, Italy.

Abstract

A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.

KEYWORDS:

ColE; Salmonella; colistin; mcr

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