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Euro Surveill. 2017 Aug 3;22(31). doi: 22846.

Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014.

Author information

1
Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.

Abstract

A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria.

KEYWORDS:

Escherichia coli; antimicrobial resistance; bacterial infections

PMID:
28797324
DOI:
22846
[Indexed for MEDLINE]
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