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Chem Commun (Camb). 2017 Aug 22;53(68):9450-9453. doi: 10.1039/c7cc04966h.

Immunoglobulin binding (B1) domain mediated antibody conjugation to quantum dots for in vitro and in vivo molecular imaging.

Author information

1
Laboratory for Nano-Bio Probes, Quantitative Biology Center (QBiC), RIKEN, Suita, Osaka 565-0874, Japan. tjin@riken.jp.

Abstract

A facile method for the preparation of antibody-quantum dot (QD) conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody-QD conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo.

PMID:
28795717
DOI:
10.1039/c7cc04966h
[Indexed for MEDLINE]

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