Send to

Choose Destination
Anal Sci. 2017;33(8):957-962. doi: 10.2116/analsci.33.957.

Development and Applications of Quantum Dot-based Molecularly Imprinted Polymer Composites for Optosensing of Carbofuran in Water.

Zhou Q1,2, Liu C3, Zhang H1,2, Zhao C3, Wang Y1,2.

Author information

Institute of Applied Ecology, Chinese Academy of Sciences.
Ministry of Agriculture Laboratory of Risk Assessment of Environment Factors for Quality and Safety of Agro-Products.
School of Pharmacy, Shenyang Pharmaceutical University.


In this paper, quantum dot (QD)-based molecularly imprinted polymer (MIP) was fabricated and successfully utilized as a fluorescent probe for highly selective and sensitive detection of carbofuran in water samples. The MIPs were synthesized followed by a multi-step swelling and polymerization method, and then labeled with CdSe/ZnS QDs via gradual solvent evaporation. Then the prepared QDs-MIP microspheres were introduced to flow cytometry by virtue of their good dispersibility in water, and fast adsorption and desorption. Under optimized conditions, the fluorescence intensity of QDs-MIP decreased linearly with the increasing of carbofuran in the concentration range of 1 - 20 μg L-1 (R2 > 0.99) and it can detect down to 0.2 μg L-1 of carbofuran. This method was simple, selective and applied successfully to the optosensing of trace carbofuran in water samples with good recoveries ranging from 94.1 ± 3.7 to 98.4 ± 4.5%.


Molecularly imprinted polymer; carbofuran; fluorescence quenching; quantum dots

Free full text

Supplemental Content

Full text links

Icon for J-STAGE, Japan Science and Technology Information Aggregator, Electronic
Loading ...
Support Center