Format

Send to

Choose Destination
Public Health Nutr. 2017 Nov;20(16):2998-3007. doi: 10.1017/S1368980017001811. Epub 2017 Aug 9.

Effects of lipid-based nutrient supplements v. micronutrient powders on nutritional and developmental outcomes among Peruvian infants.

Author information

1
1Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.
2
2Fundación Acción Contra el Hambre,Lima,Peru.
3
3Independent Consultant,Lima,Peru.
4
4Grupo de Análisis para el Desarrollo (GRADE),Lima,Peru.
5
5Ministerio de la Mujer y Poblaciones Vulnerables,Lima,Peru.
6
6Departamento de Biomedicina,Biotecnología y Salud Pública,Universidad de Cádiz,Cádiz,Spain.

Abstract

OBJECTIVE:

To determine the effects of lipid-based nutrient supplements (LNS) on children's Hb, linear growth and development, compared with supplementation with micronutrient powder (MNP).

DESIGN:

The study was a two-arm parallel-group randomized controlled trial, where participants received either LNS or MNP for daily consumption during 6 months. Supplements were delivered by staff at government-run health centres. Hb, anthropometric, motor development, language development and problem-solving indicators were measured by trained research assistants when children were 12 months of age.

SETTING:

The study was conducted in five rural districts in the Province of Ambo in the Department of Huánuco, Peru.

SUBJECTS:

We enrolled 6-month-old children (n 422) at nineteen health centres.

RESULTS:

Children who received LNS had a higher mean Hb concentration and lower odds of anaemia than those who received MNP. No significant differences in height-for-age, weight-for-height or weight-for-age Z-score, or stunting and underweight prevalence, were observed. Provision of LNS was associated with a higher pre-verbal language (gestures) score, but such effect lost significance after adjustment for covariates. Children in the LNS group had higher problem-solving task scores and increased odds of achieving this cognitive task than children in the MNP group. No significant differences were observed on receptive language or gross motor development.

CONCLUSIONS:

LNS between 6 and 12 months of age increased Hb concentration, reduced anaemia and improved cognitive development in children, but showed no effects on anthropometric indicators, motor or language development.

KEYWORDS:

Anaemia; Child development; Lipid-based nutrient supplement; Micronutrient powder; Peru; Problem solving; Stunting

PMID:
28789712
DOI:
10.1017/S1368980017001811
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Cambridge University Press
Loading ...
Support Center