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Am J Perinatol. 2018 Jan;35(1):55-58. doi: 10.1055/s-0037-1605576. Epub 2017 Aug 8.

Tale of Two Patent Ductus Arteriosus Severity Scores: Similarities and Differences.

Author information

1
Department of Pediatric Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.
2
Department of Neonatology, Rotunda Hospital, Rotunda, Dublin, Ireland.
3
Department of Pediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland.
4
Division of Neonatology, Hospital for Sick Children, Toronto, Ontario, Canada.
5
Departments of Physiology and Pediatrics, University of Toronto, Toronto, Ontario, Canada.
6
Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel.
7
Faculty of Medicine, Hebrew University, Jerusalem, Israel.

Abstract

INTRODUCTION:

Several echocardiographic scoring systems have been developed to assess the severity of patent ductus arteriosus (PDA) shunting in preterm infants.

OBJECTIVE:

The objective of this study was to compare the ability of two different scoring systems to evaluate the hemodynamic significance of the PDA and to predict long-term PDA-associated morbidities.

SUBJECTS:

El-Khuffash cohort (previously described) was derived from a multicenter, prospective, observational study conducted in tertiary neonatal intensive care units in Ireland, Canada, and Australia.

RESULTS:

A total of 141 infants with a mean gestational age of 26 ± 1.4 weeks and a mean birth weight of 952 ± 235 g were evaluated on day 2 of life. The two scores were well correlated with each other and both scores positively predicted chronic lung disease/death in this population.

CONCLUSION:

There appears to be an overall stepwise progression in the incidence of poor outcome parameters from "closed" to "borderline" to "hemodynamically significant" PDA. Both the El-Khuffash and Shaare Zedek scores are predictive of PDA-associated morbidities.

PMID:
28787748
DOI:
10.1055/s-0037-1605576
[Indexed for MEDLINE]

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