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J Cosmet Dermatol. 2017 Dec;16(4):520-526. doi: 10.1111/jocd.12393. Epub 2017 Aug 8.

Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.

Author information

1
Brazilian Center for Studies in Dermatology, Porto Algre, Brazil.
2
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
3
Collagen Research Institute (CRI), Kiel, Germany.

Abstract

BACKGROUND:

Brittle nail syndrome is a common problem among women and refers to nails that exhibit surface roughness, raggedness, and peeling.

AIM:

The goal of this study was to investigate whether daily oral supplementation with collagen peptides alleviates the symptoms of brittle nails and improves nail growth rate.

METHODS:

In this open-label, single-center trial, 25 participants took 2.5 g of specific bioactive collagen peptides (BCP, VERISOL® ) once daily for 24 weeks followed by a 4-week off-therapy period. Nail growth rate and the frequency of cracked and/or chipped nails as well as an evaluation of symptoms and global clinical improvement score of brittle nails were assessed by a physician during treatment and 4 weeks after discontinuation.

RESULTS:

Bioactive collagen peptides treatment promoted an increase of 12% nail growth rate and a decrease of 42% in the frequency of broken nails. Additionally, 64% of participants achieved a global clinical improvement in brittle nails, and 88% of participants experienced an improvement 4 weeks post-treatment. The majority of participants (80%) agreed that the use of BCP improved their nails' appearance, and were completely satisfied with the performance of the treatment.

CONCLUSIONS:

This study demonstrated that the daily ingestion of BCP increased nail growth and improved brittle nails in conjunction with a notable decrease in the frequency of broken nails.

KEYWORDS:

bioactive collagen peptides; brittle nails; collagen hydrolysate; dietary supplements; fragile nails; nail growth

PMID:
28786550
DOI:
10.1111/jocd.12393
[Indexed for MEDLINE]

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