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Microb Genom. 2016 Sep 20;2(9):e000086. doi: 10.1099/mgen.0.000086. eCollection 2016 Sep.

CLIMB (the Cloud Infrastructure for Microbial Bioinformatics): an online resource for the medical microbiology community.

Author information

1
Cardiff University School of Biosciences, The Sir Martin Evans Building, Cardiff University, Cardiff CF10 2AX, UK.
2
Institute of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, UK.
3
IT Services (Research Computing), University of Birmingham, Birmingham B15 2TT, UK.
4
Centre for Scientific Computing, University of Warwick, Coventry CV4 7AL, UK.
5
College of Medicine, Swansea University, Swansea, UK.
6
Advanced Research Computing@Cardiff (ARCCA), Cardiff University, UK.
7
Microbiology and Infection Unit, Warwick Medical School, University of Warwick, Coventry, UK.
8
The Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
#
Contributed equally

Abstract

The increasing availability and decreasing cost of high-throughput sequencing has transformed academic medical microbiology, delivering an explosion in available genomes while also driving advances in bioinformatics. However, many microbiologists are unable to exploit the resulting large genomics datasets because they do not have access to relevant computational resources and to an appropriate bioinformatics infrastructure. Here, we present the Cloud Infrastructure for Microbial Bioinformatics (CLIMB) facility, a shared computing infrastructure that has been designed from the ground up to provide an environment where microbiologists can share and reuse methods and data.

KEYWORDS:

bioinformatics; cloud computing; infrastructure; metagenomics; population genomics; virtual laboratory

PMID:
28785418
PMCID:
PMC5537631
DOI:
10.1099/mgen.0.000086
[Indexed for MEDLINE]
Free PMC Article

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