Format

Send to

Choose Destination
Sci Rep. 2017 Aug 7;7(1):7412. doi: 10.1038/s41598-017-07079-x.

Predictive clinical factors of cystoid macular edema in patients with Descemet's stripping automated endothelial keratoplasty.

Author information

1
Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
2
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
3
Baptist Eye Institute, Kyoto, Japan.
4
Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
5
Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. shigeruk@koto.kpu-m.ac.jp.
6
Baptist Eye Institute, Kyoto, Japan. shigeruk@koto.kpu-m.ac.jp.

Abstract

The purpose of this present study was to investigate predictive clinical factors associated with cystoid macular edema (CME) post Descemet's stripping automated endothelial keratoplasty (DSAEK) in a large case series. Of 393 consecutive patients who underwent DSAEK at Baptist Eye Institute, Kyoto, Japan between July 2011 and November 2016, 241 patients without CME at the pre- or early-postoperative periods were enrolled. The occurrence of anatomic CME was prospectively examined via optical coherence tomography (OCT). Possible predictive clinical factors for CME were analyzed by multivariate logistic regression analysis. At 1-month post DSAEK, CME occurred in 27 (11.2%) of the 241 patients. Multivariate analysis revealed that primary angle closure glaucoma (PACG) was significantly associated with postoperative CME (odds ratio = 6.4, P = 0.04). The findings of this study revealed that DSAEK in patients with PACG showed a high incidence of CME, thus indicating that they should undergo a careful postoperative observation of the macula via OCT.

PMID:
28785053
PMCID:
PMC5547070
DOI:
10.1038/s41598-017-07079-x
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center