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Infect Dis Clin North Am. 2017 Sep;31(3):497-511. doi: 10.1016/j.idc.2017.05.011.

Evaluation and Management of Necrotizing Soft Tissue Infections.

Author information

1
Division of Trauma and Critical Care, Department of Surgery, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07101, USA.
2
Clinical Epidemiology Section, Department of Critical Care Medicine, National Institutes of Health Clinical Center, 10 Center Drive 10/2C145, Bethesda, MD 20892, USA. Electronic address: Sameer.kadri@nih.gov.

Abstract

Despite advances in antibiotic and surgical management and supportive care for necrotizing soft tissue infections, morbidity and mortality remain substantial. Although there are clinical practice guidelines in place, there still remains much variability in choice and duration of antibiotic therapy, time to initial surgical debridement, and use of adjuvant medical therapies. This article offers an overview of necrotizing soft tissue infections with a focus on current diagnostic and treatment modalities.

KEYWORDS:

Gangrene; Necrotizing fasciitis; Sepsis; Soft tissue infection

PMID:
28779832
PMCID:
PMC5656282
DOI:
10.1016/j.idc.2017.05.011
[Indexed for MEDLINE]
Free PMC Article

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