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Skeletal Radiol. 2017 Dec;46(12):1745-1752. doi: 10.1007/s00256-017-2727-1. Epub 2017 Aug 3.

Chordoma arising from benign multifocal notochordal tumors.

Author information

1
Departments of Orthopedic Surgery and Pathology, SUNY Upstate Medical University Syracuse, Upstate Bone and Joint Center, Suite 100, 6620 Fly Road East Syracuse, New York, NY, 13057, USA.
2
Departments of Orthopedic Surgery, Pathology, and Radiology Massachusetts General Hospital, Boston, MA, USA.
3
Departments of Orthopedic Surgery and Pathology, SUNY Upstate Medical University Syracuse, Upstate Bone and Joint Center, Suite 100, 6620 Fly Road East Syracuse, New York, NY, 13057, USA. damront@upstate.edu.

Abstract

This case reports a 25-year-old woman initially diagnosed with adjacent benign notochordal cell tumors (BNCTs) of L3 and L4 based on needle biopsy of L3 and stable imaging over a 3-year period who was ultimately found to have a chordoma arising from a BNCT at L3. It illustrates the potential relationship between benign and malignant notochordal tumors and the difficulty in distinguishing them by clinical, radiological, and even histopathological means.

KEYWORDS:

Benign notochordal cell tumor; Chordoma; Lumbar; Multifocal; Spine; Vertebra

PMID:
28776089
DOI:
10.1007/s00256-017-2727-1
[Indexed for MEDLINE]

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