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J Biol Rhythms. 2017 Aug;32(4):291-294. doi: 10.1177/0748730417716685. Epub 2017 Aug 2.

Revealing Oft-cited but Unpublished Papers of Colin Pittendrigh and Coworkers.

Author information

1
Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee, USA.
2
Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
3
Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, The Netherlands.

Abstract

Among the scientific resources that Colin Pittendrigh passed on to his colleagues after his death in 1996 were two unpublished papers. These manuscripts, developed first in the mid-1960s and continually updated and refined through the late 1970s, centered on the development and experimental exploration of a model of circadian entrainment combining aspects of the well-known parametric (continuous) and nonparametric (discrete) models of entrainment. These texts reveal the experimental work surrounding Pittendrigh's determination of the limits of entrainment and the explanation of the bistability phenomenon. These manuscripts are being made publicly available in their final format (February 1978) as supplementary material to this introduction.

KEYWORDS:

Pittendrigh; mechanisms of entrainment; phase response curves; phase transition curves; photoperiodism; skeleton photoperiods; two-pulse entrainment

PMID:
28766460
PMCID:
PMC5697742
[Available on 2018-08-02]
DOI:
10.1177/0748730417716685
[Indexed for MEDLINE]

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