Format

Send to

Choose Destination
J Autism Dev Disord. 2017 Oct;47(10):3296-3310. doi: 10.1007/s10803-017-3231-0.

Accurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months.

Sturner R1,2,3, Howard B4,5, Bergmann P6,7, Morrel T5, Landa R4,8, Walton K5,9, Marks D4,10,11.

Author information

1
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. rsturner@childhealthcare.org.
2
Center for Promotion of Child Development through Primary Care, Baltimore, MD, 21210, USA. rsturner@childhealthcare.org.
3
, 6017 Altamont Place, Baltimore, MD, 21210, USA. rsturner@childhealthcare.org.
4
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
5
Total Child Health, Baltimore, MD, 21210, USA.
6
Foresight Logic, Inc., Saint Paul, MN, USA.
7
PrairieCare Institute, Minneapolis, MN, USA.
8
Kennedy Krieger Institute, Baltimore, MD, 21287, USA.
9
Baltimore Healthy Start, Baltimore, MD, 21218, USA.
10
Sinai Hospital, Baltimore, MD, 21215, USA.
11
Maternal and Child Health Unit, Public Health Division, Wyoming Department of Health, Evanston, WY, USA.

Abstract

Accuracy of autism screening using M-CHAT plus the follow-up interview (M-CHAT/F) for children screened positive at 18-months was compared to screening at 24-months. Formal ASD testing was criterion for a community sample of M-CHAT positive children (n = 98), positive predictive value (PPV) was 0.40 for the M-CHAT and 0.58 for the M-CHAT/F. MCHAT/F PPV was 0.69 among children 20+ months compared to 0.36 for <20 months. Multivariate analyses incorporating data from the Ages and Stages Questionnaire, MacArthur-Bates Communicative Development Inventory, M-CHAT and M-CHAT/F results, and M-CHAT items suggest language variables carry greatest relative importance in contributing to an age-based algorithm with potential to improve PPV for toddlers <20 months to the same level as observed in older toddlers.

KEYWORDS:

Autism screening; Developmental screening; M-CHAT; Toddler development

PMID:
28762159
PMCID:
PMC5711554
DOI:
10.1007/s10803-017-3231-0
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center