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Clin Respir J. 2018 Apr;12(4):1320-1360. doi: 10.1111/crj.12674. Epub 2017 Sep 26.

Diagnosis and treatment of community-acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical Association.

Author information

1
National Clinical Research Center of Respiratory Diseases, Center for Respiratory Diseases, China-Japan Friendship Hospital, Capital Medical University, Beijing 100029, China.
2
Department of Respiratory and Critical Care Medicine, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
3
Department of Respiratory and Critical Care Medicine, Chinese PLA General Hospital, Beijing 100853, China.
4
Department of Respiratory and Critical Care Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China.
5
Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Sichuan 610041, China.
6
Department of Pulmonary Medicine, Peking Union Medical College Hospital, Beijing 100730, China.
7
Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
8
Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
9
Department of Respiratory and Critical Care Medicine, Shengjing Hospital, China Medical University, Shenyang 110004, China.
10
Department of Respiratory Medicine, Peking University Third Hospital, Beijing 100191, China.
11
Department of Laboratory Medicine, Peking University People's Hospital, Beijing 100044, China.
12
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Diseases, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
13
Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guizhou 550002, China.
14
Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing 210002, China.

Abstract

Community-acquired pneumonia (CAP) in adults is an infectious disease with high morbidity in China and the rest of the world. With the changing pattern in the etiological profile of CAP and advances in medical techniques in diagnosis and treatment over time, Chinese Thoracic Society of Chinese Medical Association updated its CAP guideline in 2016 to address the standard management of CAP in Chinese adults. Extensive and comprehensive literature search was made to collect the data and evidence for experts to review and evaluate the level of evidence. Corresponding recommendations are provided appropriately based on the level of evidence. This updated guideline covers comprehensive topics on CAP, including aetiology, antimicrobial resistance profile, diagnosis, empirical and targeted treatments, adjunctive and supportive therapies, as well as prophylaxis. The recommendations may help clinicians manage CAP patients more effectively and efficiently. CAP in pediatric patients and immunocompromised adults is beyond the scope of this guideline. This guideline is only applicable for the immunocompetent CAP patients aged 18 years and older. The recommendations on selection of antimicrobial agents and the dosing regimens are not mandatory. The clinicians are recommended to prescribe and adjust antimicrobial therapies primarily based on their local etiological profile and results of susceptibility testing, with reference to this guideline.

KEYWORDS:

adjunctive therapy; adult; aetiology; antimicrobial therapy; community-acquired pneumonia; diagnosis; prevention

PMID:
28756639
DOI:
10.1111/crj.12674
[Indexed for MEDLINE]

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