Format

Send to

Choose Destination
J Photochem Photobiol B. 2017 Sep;174:78-83. doi: 10.1016/j.jphotobiol.2017.07.024. Epub 2017 Jul 24.

Formation of Matricaria chamomilla extract-incorporated Ag nanoparticles and size-dependent enhanced antimicrobial property.

Author information

1
Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey; Nanotechnology Research Center, Erciyes University, Kayseri, 38039, Turkey.
2
Department of Agricultural and Biological Engineering, University of Florida, 1741, Museum Road, Gainesville, FL, USA.
3
Department of Pharmaceutical Technology, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey.
4
Department of Biology, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey.
5
Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey; Nanotechnology Research Center, Erciyes University, Kayseri, 38039, Turkey. Electronic address: ismailocsoy@erciyes.edu.tr.

Abstract

Various concentrations of Matricaria chamomilla (M. chamomilla) flower extract was used for biosynthesis of Ag NPs with different sizes, 70±5 (Ag NP-1), 52±5 (Ag NP-1) and 37±4nm (Ag NP-3), and size-specific antimicrobial activity of them was evaluated towards Gram+ Staphylococcus aureus (S. aureus), Gram- Escherichia coli (E. coli) bacteria and Candida fungus albicans (C. albicans). We also examine the formation of Ag NPs as a function of the plant extract volume, Ag ion concentration (Ag+) and reaction time. M. chamomilla flower extract at 100ppm shows mild inhibitory effect by inhibiting growth of all target pathogens. The extract mediated Ag NPs even at low concentration (6.25ppm) caused reductions in cell densities of the pathogens. The potential reasons for the highly effective inhibitory activity of the extract mediated Ag NPs are: (1) synergistic effects due to combination of M. chamomile extract and Ag NP because Ag NP is an effective germicidal and M. chamomile plant itself shows mild inhibitory property, (2) high localized concentration of M. chamomile extract due to nano scale entrapment of it on surface of Ag NP and (3) size-specific antibacterial efficacy of Ag NP because small size increases the active surface area of Ag NP, which reacting bacterial cells and increases number of extract molecules anchored on the surface of Ag NP.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center