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Gac Sanit. 2018 Nov - Dec;32(6):507-512. doi: 10.1016/j.gaceta.2017.05.012. Epub 2017 Jul 26.

[Exposure to nitrogen dioxide and respiratory health at 2 years in the INMA-Valencia cohort].

[Article in Spanish]

Author information

1
Departament d'Infermeria, Universitat de València, Valencia, España.
2
Unidad Mixta de Investigación en Epidemiología y Salud Ambiental, FISABIO-Universitat Jaume I-Universitat de València, Valencia, España; CIBER de Epidemiología y Salud Pública (CIBERESP), España.
3
Departament d'Infermeria, Universitat de València, Valencia, España; Unidad Mixta de Investigación en Epidemiología y Salud Ambiental, FISABIO-Universitat Jaume I-Universitat de València, Valencia, España; CIBER de Epidemiología y Salud Pública (CIBERESP), España.
4
Departament d'Infermeria, Universitat de València, Valencia, España; Unidad Mixta de Investigación en Epidemiología y Salud Ambiental, FISABIO-Universitat Jaume I-Universitat de València, Valencia, España; CIBER de Epidemiología y Salud Pública (CIBERESP), España. Electronic address: ballester_fer@gva.es.

Abstract

OBJECTIVE:

To analyze the association between exposure to nitrogen dioxide (NO2) during pregnancy and the postnatal period up to the age of 2 years old and the incidence of respiratory problems in children from the INMA-Valencia cohort.

METHODS:

The study population included 624 children from the INMA-Valencia cohort. Individual exposure to NO2 was estimated in different environments outside the home during pregnancy and up to the age of 2 using empirical measurement and data from geo-statistical methods. Respiratory symptoms were obtained from a questionnaire applied at the age of two. The association between NO2 exposure and respiratory symptoms was performed using multivariate logistic regression.

RESULTS:

The cumulative incidence was 16.3% for persistent cough, 34.9% for wheezing and 27.6% for lower respiratory tract infections. No association was found between respiratory symptoms and exposure to NO2 in any of the children. However an association between NO2 exposure and persistent cough was found at two years of life in the children with a parental history of allergy.

CONCLUSION:

NO2 exposure would lead to persistent cough in children with a parental history of allergies.

KEYWORDS:

Air pollution; Contaminación atmosférica; Cough; Dióxido de nitrógeno; Infecciones respiratorias; Nitrogen dioxide; Respiratory tract infection; Tos

PMID:
28754341
DOI:
10.1016/j.gaceta.2017.05.012
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