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Sci Rep. 2017 Jul 25;7(1):6481. doi: 10.1038/s41598-017-06693-z.

Advantages of phylogenetic distance based constrained ordination analyses for the examination of microbial communities.

Author information

1
Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA.
2
Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA. oleg.paliy@wright.edu.

Abstract

Recently developed high throughput molecular techniques such as massively parallel sequencing and phylogenetic microarrays generate vast datasets providing insights into microbial community structure and function. Because of the high dimensionality of these datasets, multivariate ordination analyses are often employed to examine such data. Here, we show how the use of phylogenetic distance based redundancy analysis provides ecological interpretation of microbial community differences. We also extend the previously developed method of principal response curves to incorporate phylogenetic distance measure, and we demonstrate the improved ability of this approach to provide ecologically relevant insights into temporal alterations of microbial communities.

PMID:
28743891
PMCID:
PMC5526943
DOI:
10.1038/s41598-017-06693-z
[Indexed for MEDLINE]
Free PMC Article

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