Format

Send to

Choose Destination
Trends Cancer. 2016 Jun;2(6):277-279. doi: 10.1016/j.trecan.2016.04.005. Epub 2016 May 6.

Cancer-Associated Fibroblasts: Perspectives in Cancer Therapy.

Author information

1
Targeted Therapeutics, Biomaterials Science and Technology, MIRA Institute of Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands. Electronic address: j.prakash@utwente.nl.

Abstract

The interplay between cancer cells and stromal cells is increasingly recognized as a main driver of tumor progression and metastasis. This Forum article highlights the role of cancer-associated stromal fibroblasts (CAFs) in tumorigenesis and discusses the potential for developing specific stromal cancer therapies.

KEYWORDS:

cancer therapy; cancer-associated fibroblasts; exosomes; miRNA; tumor stroma

PMID:
28741524
DOI:
10.1016/j.trecan.2016.04.005
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center