Transcatheter Therapy for Mitral Regurgitation Clinical Challenges and Potential Solutions

Circulation. 2017 Jul 25;136(4):404-417. doi: 10.1161/CIRCULATIONAHA.117.025264.

Abstract

Severe mitral regurgitation is a common and complex disease that is associated with an adverse prognosis. For decades, surgical treatment has been the standard of care. Recently, multiple technologies for transcatheter mitral therapy have emerged, with the potential for both repair and replacement in patients with native mitral regurgitation. Transcatheter mitral technologies have potential as solutions for unmet clinical needs. Further rigorous clinical studies are needed to determine their efficacy and safety, as well as the appropriate patient candidates. These evaluations will help to define the role of transcatheter mitral therapy as a potentially exciting new strategy to improve the lives of patients with mitral regurgitation.

Keywords: mitral; regurgitation; repair; replacement; surgery; transcatheter.

Publication types

  • Review

MeSH terms

  • Cardiac Catheterization / methods*
  • Cardiac Catheterization / trends
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / trends
  • Humans
  • Mitral Valve Insufficiency / diagnostic imaging*
  • Mitral Valve Insufficiency / surgery*