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J Am Geriatr Soc. 2017 Oct;65(10):2227-2234. doi: 10.1111/jgs.14990. Epub 2017 Jul 22.

Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials.

Chiu HL1, Chan PT2, Chu H3,4,5, Hsiao SS6, Liu D7, Lin CH8,9, Chou KR1,10,11.

Author information

1
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
2
Department of Nursing, En Chu Kong Hospital, Taipei, Taiwan.
3
Aviation Physiology Research Laboratory, Gangshan Branch, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.
4
Institute of Aerospace and Undersea Medicine, School of Medicine, Taipei, Taiwan.
5
Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
6
Department of Nursing, Taipei Medical University Hospital, Taipei, Taiwan.
7
Department of Nursing, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
8
School of Gerontology Health Management, College of Nursing, Taipei Medical University, Taipei, Taiwan.
9
Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan.
10
Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
11
Department of Nursing, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.

Abstract

OBJECTIVES:

To explore the effects of light therapy on behavioral disturbances (BDs), sleep quality, and depression.

DESIGN:

Meta-analysis of randomized controlled trials.

SETTING:

PubMed, Cochrane Library, Medline, EMBASE, Web of Science, and clinicaltrials.gov of selected randomized controlled trials and previous systematic reviews were searched.

PARTICIPANTS:

Cognitively impaired persons.

MEASUREMENTS:

Information was extracted on study characteristics, quality assessment, and outcomes. Outcome measures included BDs, sleep quality, and depression.

RESULTS:

Nine randomized controlled trials were examined. The results showed that light therapy has a moderate effect on BD (g = -0.61) and depression (g = -0.58) and a small effect on total sleep time at night (g = 0.25). Subgroup analysis indicated that a light intensity of 2,500 lux or greater has a greater effect on depression than an intensity of less than 2,500 lux (P = .03), and the low risk of bias in blinding was superior to the RCTs deemed to be of high or unclear risk of bias in blinding in terms of BD (P = .02).

CONCLUSION:

Light therapy can relieve BD, improve sleep quality, and alleviate symptoms of depression for cognitively impaired persons.

KEYWORDS:

behavioral disturbance; cognitively impaired; depression; light therapy; sleep quality

PMID:
28734045
DOI:
10.1111/jgs.14990
[Indexed for MEDLINE]

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