Format

Send to

Choose Destination
J Clin Microbiol. 2017 Oct;55(10):2884-2893. doi: 10.1128/JCM.00489-17. Epub 2017 Jul 19.

The Human Virome: Implications for Clinical Practice in Transplantation Medicine.

Author information

1
Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA susietan@stanford.edu.
2
Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.
3
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
4
Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.
5
Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

Abstract

Advances in DNA sequencing technology have provided an unprecedented opportunity to study the human virome. Transplant recipients and other immunocompromised hosts are at particular risk for developing virus-related pathology; thus, the impact of the virome on health and disease may be even more relevant in this population. Here, we discuss technical considerations in studying the human virome, the current literature on the virome in transplant recipients, and near-future applications of sequence-based findings that can further our understanding of viruses in transplantation medicine.

KEYWORDS:

immunocompromised hosts; transplantation; virome

PMID:
28724557
PMCID:
PMC5625374
DOI:
10.1128/JCM.00489-17
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center