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Curr Stem Cell Res Ther. 2018;13(7):583-590. doi: 10.2174/1574888X12666170718152611.

Research Progress of the Types and Preparation Techniques of Scaffold Materials in Cartilage Tissue Engineering.

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School of Stomatology, Hospital of Stomatology, Tianjin Medical University, Tianjin, China.
Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.


The management of chondral defects has been a challenge for a long time because of the poor self-healing capacity of articular cartilage. Many approaches ranging from symptomatic treatment to structural cartilage regeneration are not that successful with very limited satisfactory results. Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. The appearance of cartilage tissue engineering has brought good news for cartilage defect repair. Through this review, we are aimed at reviewing the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.


Chondral defect; cartilage tissue engineering; collagen; scaffold; scaffold fabrication technology; scaffold materials.

[Indexed for MEDLINE]

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