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J Med Case Rep. 2017 Jul 17;11(1):194. doi: 10.1186/s13256-017-1359-3.

Resectable adenocarcinoma developing in the remnant pancreas 7 years after partial pancreatoduodenectomy for invasive ductal adenocarcinoma of the pancreas: a case report.

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Clinic for Visceral and Thoracic Surgery, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Clinic for Visceral and Thoracic Surgery, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Institute for Pathology, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.



Pancreatic adenocarcinoma still has an excessively high mortality rate and resection is the only potentially curative treatment. The postoperative 5-year survival rate is approximately 20% and recurrence develops generally within 2 years. We report a case of a localized recurrent pancreatic adenocarcinoma in the remnant pancreas, 7 years after initial resection.


In 2008 an abdominal computed tomography scan showed a mass in the pancreas of a 70-year-old white woman, who presented with occlusive jaundice and abdominal pain in her right upper quadrant. A pancreatoduodenectomy was performed for a clinically suspected pancreatic adenocarcinoma. Histology confirmed a ductal adenocarcinoma. Afterwards, she received adjuvant chemotherapy with gemcitabine. In 2015 a follow-up positron emission tomography-computed tomography scan showed a single lesion in her remnant pancreas. Subsequently, a partial re-resection was performed. Histology confirmed once again a ductal adenocarcinoma. She received adjuvant chemotherapy with gemcitabine again and is still alive almost 9 years after she had first been diagnosed as having pancreatic cancer.


In selected cases re-resection for pancreatic recurrence is feasible and provides a survival benefit. In cases involving late recurrence, it is difficult to distinguish between true recurrence and the development of a new tumor. In order to detect recurrences at an early stage in long-term survivors, follow-up needs to occur on a regular and long-term basis.


Long-term survivors; Recurrent pancreatic adenocarcinoma; Repeat pancreatectomy

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