Send to

Choose Destination
Nat Rev Genet. 2017 Oct;18(10):581-598. doi: 10.1038/nrg.2017.49. Epub 2017 Jul 17.

Evolutionary biology through the lens of budding yeast comparative genomics.

Author information

Institut de Biologie Intégrative et des Systèmes, Département de Biologie, PROTEO, Université Laval, Pavillon Charles-Eugene-Marchand, 1030 Avenue de la Médecine, Québec, Quebec G1V 0A6, Canada.
Département des Sciences Biologiques, Pavillon Marie-Victorin, 90 rue Vincent d'Indy, Université de Montréal, Montréal, Quebec H2V 2S9, Canada.
Département des Sciences des aliments, Institut sur la nutrition et les aliments fonctionnels (INAF), Université Laval, Québec G1V 0A6, Quebec, Canada.


The budding yeast Saccharomyces cerevisiae is a highly advanced model system for studying genetics, cell biology and systems biology. Over the past decade, the application of high-throughput sequencing technologies to this species has contributed to this yeast also becoming an important model for evolutionary genomics. Indeed, comparative genomic analyses of laboratory, wild and domesticated yeast populations are providing unprecedented detail about many of the processes that govern evolution, including long-term processes, such as reproductive isolation and speciation, and short-term processes, such as adaptation to natural and domestication-related environments.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center