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An Pediatr (Barc). 2018 May;88(5):273-279. doi: 10.1016/j.anpedi.2017.06.002. Epub 2017 Jul 12.

[Congenital heart disease mortality in Spain during a 10 year period (2003-2012)].

[Article in Spanish]

Author information

1
Cardiología Infantil, Área de Pediatría y Neonatología, Hospital Universitario Fundación Alcorcón, Alcorcón (Madrid), España. Electronic address: fjplescure@fhalcorcon.es.
2
Unidad de Medicina Preventiva, Hospital Universitario Fundación Alcorcón, Alcorcón (Madrid), España.
3
Subdirección de Epidemiología, Dirección General de Salud Pública, Departamento de Salud, Consejería de Sanidad, Madrid, España.
4
Cardiología Infantil, Área de Pediatría y Neonatología, Hospital Universitario Fundación Alcorcón, Alcorcón (Madrid), España.

Abstract

INTRODUCTION AND OBJECTIVES:

Congenital heart disease is a major cause of infant mortality in developed countries. In Spain, there are no publications at national level on mortality due to congenital heart disease. The aim of this study is to analyse mortality in infants with congenital heart disease, lethality of different types of congenital heart disease, and their variation over a ten-year period.

METHODS:

A retrospective observational study was performed to evaluate mortality rate of children under one year old with congenital heart disease, using the minimum basic data set, from 2003 to 2012. Mortality rate and relative risk of mortality were estimated by Poisson regression.

RESULTS:

There were 2,970 (4.58%) infant deaths in a population of 64,831 patients with congenital heart disease, with 73.8% of deaths occurring during first week of life. Infant mortality rate in patients with congenital heart disease was 6.23 per 10,000 live births, and remained constant during the ten-year period of the study, representing 18% of total infant mortality rate in Spain. The congenital heart diseases with highest mortality rates were hypoplastic left heart syndrome (41.4%), interruption of aortic arch (20%), and total anomalous pulmonary drainage (16.8%). Atrial septal defect (1%) and pulmonary stenosis (1.1%) showed the lowest mortality rate.

CONCLUSIONS:

Congenital heart disease was a major cause of infant mortality with no variations during the study period. The proportion of infants who died in our study was similar to other similar countries. In spite of current medical advances, some forms of congenital heart disease show very high mortality rates.

KEYWORDS:

Cardiopatías congénitas; Congenital heart defect; Epidemiology; Epidemiología; Infant mortality rate; Mortalidad infantil

PMID:
28711428
DOI:
10.1016/j.anpedi.2017.06.002
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