Format

Send to

Choose Destination
Brain Topogr. 2018 Mar;31(2):161-173. doi: 10.1007/s10548-017-0576-9. Epub 2017 Jul 13.

Parcellation of Macaque Cortex with Anatomical Connectivity Profiles.

Wang J1, Zuo Z2, Xie S3,4, Miao Y2, Ma Y5, Zhao X6, Jiang T7,8,9,10.

Author information

1
Key Laboratory for NeuroInformation of the Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 625014, China. jiaojianwang@uestc.edu.cn.
2
State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
3
Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
4
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
5
Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, China.
6
State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. xdzhao@bcslab.ibp.ac.cn.
7
Key Laboratory for NeuroInformation of the Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 625014, China. jiangtz@nlpr.ia.ac.cn.
8
Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China. jiangtz@nlpr.ia.ac.cn.
9
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China. jiangtz@nlpr.ia.ac.cn.
10
CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China. jiangtz@nlpr.ia.ac.cn.

Abstract

The macaque model has been widely used to investigate the brain mechanisms of specific cognitive functions and psychiatric disorders. However, a detailed functional architecture map of the macaque cortex in vivo is still lacking. Here, we aimed to construct a new macaque cortex atlas based on its anatomical connectivity profiles using in vivo diffusion MRI. First, we defined the macaque cortical seed areas using the NeuroMaps atlas. Then, we applied the anatomical connectivity patterns-based parcellation approach to parcellate the macaque cortex into 80 subareas in each hemisphere, which were approximately symmetric between the two hemispheres. In each hemisphere, we identified 14 subareas in the frontal cortex, 9 subareas in the somatosensory cortex, 13 subareas in the parietal cortex, 16 subareas in the temporal cortex, 16 subareas in the occipital cortex, and 12 subareas in the limbic system. Finally, the graph-based network analyses of the anatomical network based on newly constructed macaque cortex atlas identified seven hub areas including bilateral ventral premotor cortex, bilateral superior parietal lobule, right medial precentral gyrus, and right precuneus. This newly constructed macaque cortex atlas may facilitate studies of the structure and functions of the macaque brain in the future.

KEYWORDS:

Anatomical connectivity profiles; Cortex atlas; Hub; Macaque; Parcellation

PMID:
28707157
DOI:
10.1007/s10548-017-0576-9
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center