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PLoS One. 2017 Jul 13;12(7):e0180970. doi: 10.1371/journal.pone.0180970. eCollection 2017.

Dosimetric characteristics of a reusable 3D radiochromic dosimetry material.

Park JM1,2,3,4, Park SY1,2,3, Choi CH1,2,3, Chun M1,2,3, Han JH1,3, Cho JD1,3, Kim JI1,2,3.

Author information

Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea.
Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.
Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Center for Convergence Research on Robotics, Advance Institutes of Convergence Technology, Suwon, Korea.



To investigate the dosimetric characteristics of PRESAGEREU dosimeters.


Commercially available PRESAGEREU dosimeters (size of 10 mm × 10 mm × 45 mm) were divided into two groups, with one of the groups placed at room temperature of 22°C (RT group) and another group placed at low temperature of 10°C (LT group). A total of 3 dosimeters (set of dosimeters) were irradiated at a time, with doses of 1 Gy, 2 Gy, 4 Gy, 8 Gy, 12 Gy, 16 Gy, and 20 Gy, at a nominal dose rate of 400 MU/min at temperature of 22°C. The dosimeters were irradiated three additional times by delivering the same doses as those during the initial irradiations (4 irradiation cycles). Optical density (OD) was assessed using optical CT scanning.


Considering both linearity and sensitivity of the OD curves, R2 above 0.95 and sensitivity above 0.04 ΔOD/Gy were observed at the 1st irradiation (reading time ≤ 6 h) and 2nd irradiation (reading time = 0.5 h) for the RT group. For the LT group, those values were observed at the 1st irradiation (reading time ≤ 2 h), and the 3rd and 4th irradiations (both reading times = 0.5 h). Considering the reproducibility of signals in response to the same dose, dosimeters in the RT group showed average deviations among dosimeters less than 5% (the 1st and 2nd irradiations at the reading time of 0.5 h), while for dosimeters in the LT group showed average deviations among dosimeters less than 6% (the 3rd and 4th irradiations at the reading time of 0.5 h). For the rest, the OD curves were not linear, sensitivities of the dosimeters were lower than 0.04 ΔOD/Gy, and OD deviations at the same dose were larger than 6%.


At room temperature, PRESAGEREU dosimeters could be used for dose measurement only for up to two dose measurement sessions. At low temperatures, usage of PRESAGEREU dosimeters for dose measurement seems to be possible from the 3rd irradiation. When reusing PRESAGEREU dosimeters, the OD curve should be re-defined for every measurement session because the shape of this curve depends on the irradiation history.

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