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Clin Ter. 2017 Jul-Aug;168(4):e271-e277. doi: 10.7417/T.2017.2019.

[Risk factors' analysis of transient and permanent hypoparathyroidism after thyroidectomy].

[Article in Italian]

Author information

1
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", Palermo.
2
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", Palermo - Dipartimento di Discipline Chirurgiche, Oncologiche e Stomatologiche, Università degli Studi di Palermo, Italia.
3
Dipartimento di Discipline Chirurgiche, Oncologiche e Stomatologiche, Università degli Studi di Palermo, Italia.

Abstract

AIMS:

This review evaluates those main risk factors that can affect patients undergoing thyroidectomy, to reach a better pre- and post-operative management of transient and permanent hypoparathyroidism.

DISCUSSION:

The transient hypoparathyroidism is a potentially severe complication of thyroidectomy, including a wide range of signs and symptoms that persists for a few weeks. The definitive hypoparathyroidism occurs when a medical treatment is necessary over 12 months. Risk factors that may influence the onset of this condition after thyroidectomy include: pre- and post-operative biochemical factors, such as serum calcium levels, vitamin D blood concentrations and intact PTH. Other involved factors could be summarized as follow: female sex, Graves' or thyroid neoplastic diseases, surgeon's dexterity and surgical technique. The medical treatment includes the administration of calcium, vitamin D and magnesium sometimes.

CONCLUSIONS:

Although biological and biochemical factors could be related to iatrogenic hypoparathyroidism, the surgeon's experience and the used surgical technique still maintain a crucial role in the aetiology of this important complication.

KEYWORDS:

Calcium; Hipoparathyroidism; Parathyroid hormone; Risk factors; Thyroidectomy

PMID:
28703844
DOI:
10.7417/T.2017.2019
[Indexed for MEDLINE]
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