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Dev Genes Evol. 2017 Jul;227(4):245-252. doi: 10.1007/s00427-017-0585-4. Epub 2017 Jul 11.

Spatiotemporal expression of a twist homolog in the leech Helobdella austinensis.

Author information

1
School of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
2
Department of Life Sciences, Chung-Ang University, Seoul, 156-756, Republic of Korea.
3
Department of Molecular and Cell Biology, 385 LSA, University of California, Berkeley, CA, 94720-3200, USA.
4
Department of Molecular and Cell Biology, 385 LSA, University of California, Berkeley, CA, 94720-3200, USA. weisblat@berkeley.edu.
5
School of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea. sjchobio@chungbuk.ac.kr.
6
Department of Molecular and Cell Biology, 385 LSA, University of California, Berkeley, CA, 94720-3200, USA. sjchobio@chungbuk.ac.kr.

Abstract

Genes of the twist family encode bHLH transcription factors known to be involved in the regulation and differentiation of early mesoderm. Here, we report our characterization of Hau-twist, a twist homolog from the leech Helobdella austinensis, a tractable lophotrochozoan representative. Hau-twist was expressed in segmental founder cells of the mesodermal lineage, in subsets of cells within the mesodermal lineage of the germinal plate, in circumferential muscle fibers of a provisional integument during segmentation and organogenesis stages and on the ventral side of the developing proboscis. Thus, consistent with other systems, our results suggest that twist gene of the leech Helobdella might function in mesoderm differentiation.

KEYWORDS:

Leech; Lophotrochozoa; Mesoderm; twist gene

PMID:
28699036
PMCID:
PMC5637724
DOI:
10.1007/s00427-017-0585-4
[Indexed for MEDLINE]
Free PMC Article

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