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Dev Cell. 2017 Jul 10;42(1):1-2. doi: 10.1016/j.devcel.2017.06.018.

Lipid Droplets Guard Mitochondria during Autophagy.

Author information

1
Zellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany. Electronic address: till.klecker@uni-bayreuth.de.
2
Zellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany.

Abstract

In this issue of Developmental Cell, Nguyen et al. (2017) show that lipid droplets serve a dual purpose during starvation. First, they act as an energy source by supplying fatty acids for mitochondrial β oxidation. Second, they sequester toxic lipids that arise during autophagic degradation of membranous organelles, thereby protecting mitochondria.

PMID:
28697329
DOI:
10.1016/j.devcel.2017.06.018
[Indexed for MEDLINE]
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